{
  "slug": "therapeutic-applications-of-igy-in-common-canine-and-feline-vi-41245806",
  "source": {
    "title": "Therapeutic applications of IgY in common canine and feline viral diseases.",
    "journal": "Veterinary and animal science",
    "year": 2025,
    "doi": "10.1016/j.vas.2025.100534",
    "pmid": "41245806",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "The reviewed feline IgY evidence came from a single core research group and had not been independently replicated.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Evidence related to the therapeutic benefits of IgY in feline viral infections entirely came from the same core research group led by T.D. Supeanu and A. Supeanu and had not been independently replicated by other researchers.",
      "review_status": "PASSED"
    },
    {
      "statement": "The IgY preparations used in the reviewed feline studies did not target feline viral particles.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "The IgY used in feline trials was non-specific, did not target viral particles, and was used to treat against a range of viral infections (FIV/FeLV/FIP), which may have limited its efficacy.",
      "review_status": "PASSED"
    },
    {
      "statement": "Whether FeLV-specific IgY can neutralize the virus and alleviate viremia remains a research question in this review.",
      "epistemic_type": "OPEN_QUESTION",
      "evidence_level": null,
      "confidence": "100",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    },
    {
      "statement": "The review could not determine whether weak feline findings reflected the non-specific IgY product or limitations of study design and sample size.",
      "epistemic_type": "OPEN_QUESTION",
      "evidence_level": null,
      "confidence": "100",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-PHARMA-005",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-10-31 11:30 UTC",
    "updated_iso": "2026-10-31T11:30:31Z"
  }
}