{
  "slug": "suspected-chronic-eosinophilic-leukemia-in-a-cat-treated-with-42504294",
  "source": {
    "title": "Suspected chronic eosinophilic leukemia in a cat treated with toceranib.",
    "journal": "JFMS open reports",
    "year": 2026,
    "doi": "10.1177/20551169261460751",
    "pmid": "42504294",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "The authors considered possible transformation from HES of unknown significance to CEL as an explanation for the initially indolent disease course.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "This cat initially exhibited an indolent disease course, possibly reflecting transformation from HES of unknown significance to CEL, supporting a disease continuum.",
      "review_status": "PASSED"
    },
    {
      "statement": "Idiopathic HES could not be excluded because bone marrow biopsy was declined and only one myeloblast was observed.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "However, due to client-declined bone marrow biopsy and only one myeloblast cell observed, idiopathic HES could not be ruled out.",
      "review_status": "PASSED"
    },
    {
      "statement": "In the reported cat, infectious disease testing that included FeLV was negative.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Infectious disease testing (feline leukemia virus [FeLV]/feline immunodeficiency virus, heartworm antigen) was negative.",
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-ONCOLOGY-004",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-10-31 11:30 UTC",
    "updated_iso": "2026-10-31T11:30:30Z"
  }
}