{
  "slug": "retrovirus-induced-immunosuppression-role-of-the-transmembrane-42515592",
  "source": {
    "title": "Retrovirus-Induced Immunosuppression: Role of the Transmembrane Envelope Protein.",
    "journal": "Viruses",
    "year": 2026,
    "doi": "10.3390/v18070740",
    "pmid": "42515592",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "Whether immunosuppressive-domain signaling involves the Ras-Raf-MEK-MAPK and PI3K-AKT-mTOR pathways remains unconfirmed.",
      "epistemic_type": "OPEN_QUESTION",
      "evidence_level": null,
      "confidence": "100",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    },
    {
      "statement": "The identity of the receptor for the retroviral immunosuppressive domain remains unresolved.",
      "epistemic_type": "OPEN_QUESTION",
      "evidence_level": null,
      "confidence": "100",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-VIROLOGY-001",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-10-31 11:30 UTC",
    "updated_iso": "2026-10-31T11:30:30Z"
  }
}