{
  "slug": "retrospective-analysis-of-feline-leukemia-virus-felv-frequency-40427346",
  "source": {
    "title": "Retrospective Analysis of Feline Leukemia Virus (FeLV) Frequency in Domestic Cats in Quito, Ecuador (2021-2024).",
    "journal": "Animals : an open access journal from MDPI",
    "year": 2025,
    "doi": "10.3390/ani15101469",
    "pmid": "40427346",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "Cats aged 1–5 years accounted for 54.32% of FeLV-positive cases, but the authors reported no statistically significant differences among age groups.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Regarding the ages of FeLV-positive animals, 54.32% (132/243) were cats between 1 and 5 years old, 22.22% (54/243) were between 1 month and 11 months, 18.52% (45/243) between 5 and 10 years, and 4.94% (12/243) between 10 and 19 years ( Table 2 ), with no statistically significant differences among age groups ( p = 0.22).",
      "review_status": "PASSED"
    },
    {
      "statement": "RT-qPCR identified FeLV positivity in 243 patients (28.59%) and negativity in 607 patients (71.41%) in the included dataset.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Regarding the presence of the virus in the samples, RT-qPCR determined that 243 patients (28.59%) tested positive for the virus, while 607 patients (71.41%) tested negative for the feline leukemia virus ( Table 1 ).",
      "review_status": "PASSED"
    },
    {
      "statement": "The study retrospectively evaluated 850 eligible cat analyses from veterinary centers in Quito, using records that contained sex, date of birth, test result, and sample type.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "This is an observational, retrospective study based on laboratory analyses conducted between September 2021 and December 2024, on animals treated at veterinary centers in Quito, Ecuador. Inclusion criteria were laboratory reports that included the patient’s sex, date of birth, test result, and sample type. Records that did not contain all this information were eliminated. A total of 850 cat analyses met the inclusion criteria and were evaluated, which included information on sex, date of birth of the patient, test results, and the type of sample obtained.",
      "review_status": "PASSED"
    },
    {
      "statement": "The reported FeLV detection frequencies cannot establish the incidence or mechanisms of FeLV-associated lymphoma or leukemia in this cohort.",
      "epistemic_type": "INFERENCE",
      "evidence_level": null,
      "confidence": "99",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-ONCOLOGY-004",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-10-31 11:30 UTC",
    "updated_iso": "2026-10-31T11:30:31Z"
  }
}