{
  "slug": "follow-up-of-viral-parameters-in-felv-or-fiv-naturally-infecte-31514435",
  "source": {
    "title": "Follow-Up of Viral Parameters in FeLV- or FIV-Naturally Infected Cats Treated Orally with Low Doses of Human Interferon Alpha.",
    "journal": "Viruses",
    "year": 2019,
    "doi": "10.3390/v11090845",
    "pmid": "31514435",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "In FIV-infected cats, antigenemia or reverse transcriptase activity was below detection limits, and the reported effect on proviral load was less marked than in FeLV-infected cats.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "The level of antigenemia or RT activity was below the detection limits in FIV+ cats, and the effect on proviral load was less marked than in FeLV+ cats.",
      "review_status": "PASSED"
    },
    {
      "statement": "The study enrolled 27 naturally FeLV-infected cats and 31 naturally FIV-infected cats.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Twenty-seven FeLV-infected cats (FeLV+) and 31 FIV-infected cats (FIV+) were enrolled in the study.",
      "review_status": "PASSED"
    },
    {
      "statement": "Whether rHuIFN-α changes the progression of feline infection remains unresolved in light of the rebound observed after discontinuation.",
      "epistemic_type": "OPEN_QUESTION",
      "evidence_level": null,
      "confidence": "100",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-PHARMA-005",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-10-31 11:30 UTC",
    "updated_iso": "2026-10-31T11:30:30Z"
  }
}