{
  "slug": "first-molecular-detection-of-leishmania-infantum-in-a-domestic-42312125",
  "source": {
    "title": "First molecular detection of Leishmania infantum in a domestic cat from Costa Rica.",
    "journal": "JFMS open reports",
    "year": 2026,
    "doi": "10.1177/20551169261445126",
    "pmid": "42312125",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "The authors could not exclude persistence of Leishmania infection at sites other than the excised lesion.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Moreover, the absence of lesion recurrence after surgical excision, despite the lack of anti- Leishmania treatment, suggests local clinical control; however, persistence of infection at other sites could not be excluded.",
      "review_status": "PASSED"
    },
    {
      "statement": "The cat's initial point-of-care FeLV antigen and FIV antibody tests were negative, but scheduled-interval follow-up testing was not performed.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Point-of-care testing for feline leukemia virus (FeLV) antigen and feline immunodeficiency virus (FIV) antibodies was performed using a commercial rapid immunochromatographic kit (FIVab/FeLV AG Test Kit; BioNote), and both results were negative. Follow-up testing in 30 days (FeLV) and 60 days (FIV) was not performed.",
      "review_status": "PASSED"
    },
    {
      "statement": "Sequencing of the lesion PCR product showed 99.62% identity with the L infantum reference sequence MG778653.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Sequencing of the PCR product showed 99.62% identity with L infantum (GenBank accession number MG778653 ), previously isolated from a naturally infected dog in Brazil.",
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-PHARMA-005",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-10-31 11:30 UTC",
    "updated_iso": "2026-10-31T11:30:31Z"
  }
}