{
  "slug": "feline-lymphoma-associated-with-feline-leukemia-virus-felv-and-41111634",
  "source": {
    "title": "Feline lymphoma associated with feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) infections in Brazil- Systematic review.",
    "journal": "Veterinary and animal science",
    "year": 2025,
    "doi": "10.1016/j.vas.2025.100514",
    "pmid": "41111634",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "The authors identify geographical reporting bias, with southern and southeastern Brazilian research centers overrepresented.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Middle- to high-income areas, where feline medicine and veterinary pathology research groups are concentrated, are overrepresented in the South and Southeast regions. This creates an inherent bias, as these regions have more available data compared to lower-income areas",
      "review_status": "PASSED"
    },
    {
      "statement": "The review lacked a comparison group of cats without lymphoma.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "The absence of a control group comprising FeLV-positive and FeLV-negative/FIV-negative cats without lymphoma is a limitation of this review, which focused solely on confirmed lymphoma cases",
      "review_status": "PASSED"
    },
    {
      "statement": "Among reviewed lymphoma cases, FeLV-positive status was significantly associated with mediastinal lymphoma.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "99",
      "evidence_excerpt": "Mediastinal 77 46.4 8 8.7 85 32.9 < 0.0001 * 9.084 (4.170 to 19.070) *",
      "review_status": "PASSED"
    },
    {
      "statement": "Gastrointestinal lymphoma was less frequent among FeLV-positive lymphoma cases than among FeLV-negative/FIV-negative lymphoma cases.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "99",
      "evidence_excerpt": "Gastrointestinal 15 9.0 51 55.4 66 25.6 < 0.0001 * 0.079 (0.042 to 0.159) *",
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-ONCOLOGY-004",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "gpt-6.1-sol",
    "updated": "2026-11-02 11:20 UTC",
    "updated_iso": "2026-11-02T11:20:26Z"
  }
}