{
  "slug": "comparative-prognostic-performance-of-quick-sequential-organ-f-42344338",
  "source": {
    "title": "Comparative prognostic performance of quick sequential organ failure assessment, lactate, systemic inflammatory response syndrome criteria, and neutrophil-to-lymphocyte ratio for mortality prediction in critically ill dogs and cats.",
    "journal": "Veterinary world",
    "year": 2026,
    "doi": "10.14202/vetworld.2026.2208-2220",
    "pmid": "42344338",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "This study prospectively evaluated 76 critically ill client-owned dogs and cats, including 37 cats, admitted to a critical-care unit.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "97",
      "evidence_excerpt": "A prospective cohort study was conducted on 76 client-owned critically ill animals, including 39 dogs and 37 cats, admitted to the CCU of the Small Animal Hospital, Chiang Mai University, Thailand.",
      "review_status": "PASSED"
    },
    {
      "statement": "The primary outcome was survival status 21 days after admission.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "98",
      "evidence_excerpt": "Survival status at 21 days post-admission was used as the primary outcome measure.",
      "review_status": "PASSED"
    },
    {
      "statement": "Overall 21-day survival was 47.4%, with 43.2% survival reported in cats.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "98",
      "evidence_excerpt": "The overall 21-day survival rate was 47.4%, with survival rates of 51.3% in dogs and 43.2% in cats.",
      "review_status": "PASSED"
    },
    {
      "statement": "qSOFA showed the best prognostic performance among the evaluated markers for mortality prediction in this cohort, with AUC 0.72.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "96",
      "evidence_excerpt": "qSOFA demonstrated the best prognostic performance for mortality prediction, with an AUC of 0.72 (95% confidence interval [CI]: 0.61-0.82).",
      "review_status": "PASSED"
    },
    {
      "statement": "Adding lactate to qSOFA produced a slightly higher AUC, but the improvement was not statistically significant.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "98",
      "evidence_excerpt": "The combined qSOFA+lactate model produced a slightly higher AUC of 0.75 (95% CI: 0.62-0.88), although the improvement was not statistically significant.",
      "review_status": "PASSED"
    },
    {
      "statement": "SIRS and NLR had limited discriminative ability and poor overall predictive performance in this study.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "97",
      "evidence_excerpt": "SIRS and NLR exhibited limited discriminative ability and poor overall predictive performance.",
      "review_status": "PASSED"
    },
    {
      "statement": "The findings are only indirectly relevant to FeLV because the source does not state that any cats had FeLV or that FeLV-specific outcomes were assessed.",
      "epistemic_type": "INFERENCE",
      "evidence_level": null,
      "confidence": "95",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    },
    {
      "statement": "Whether qSOFA, lactate, SIRS, or NLR predict mortality specifically in FeLV-positive cats remains unknown from this source.",
      "epistemic_type": "OPEN_QUESTION",
      "evidence_level": null,
      "confidence": "96",
      "evidence_excerpt": null,
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-VIROLOGY-001",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-08-31 19:45 UTC",
    "updated_iso": "2026-08-31T19:45:16Z"
  }
}