{
  "slug": "a-retrospective-examination-of-feline-leukemia-subgroup-charac-29320424",
  "source": {
    "title": "A Retrospective Examination of Feline Leukemia Subgroup Characterization: Viral Interference Assays to Deep Sequencing.",
    "journal": "Viruses",
    "year": 2018,
    "doi": "10.3390/v10010029",
    "pmid": "29320424",
    "content_access_status": "FULL_TEXT_OA"
  },
  "claims": [
    {
      "statement": "FeLV is associated with multiple fatal disease syndromes in cats, including lymphoma.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "Feline leukemia virus (FeLV) was the first feline retrovirus discovered, and is associated with multiple fatal disease syndromes in cats, including lymphoma.",
      "review_status": "PASSED"
    },
    {
      "statement": "The review discusses how viral interference assays, Sanger sequencing, PCR, and next-generation sequencing have sequentially defined FeLV classification, transmission, and disease-inducing potential.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "In this review, we discuss how FeLV classification, transmission, and disease-inducing potential have been defined sequentially by viral interference assays, Sanger sequencing, PCR, and next-generation sequencing.",
      "review_status": "PASSED"
    },
    {
      "statement": "The authors identify the influences of endogenous FeLV and host genetics as opportunities for future FeLV research.",
      "epistemic_type": "EVIDENCE",
      "evidence_level": "C",
      "confidence": "100",
      "evidence_excerpt": "In particular, we highlight the influences of endogenous FeLV and host genetics that represent FeLV research opportunities on the near horizon.",
      "review_status": "PASSED"
    }
  ],
  "provenance": {
    "agent": "AVAPROJECT-ONCOLOGY-004",
    "critic": "AVAPROJECT-CRITIC-001",
    "model": "openai-codex",
    "updated": "2026-10-31 11:30 UTC",
    "updated_iso": "2026-10-31T11:30:31Z"
  }
}